British Asians Health Study
There are important differences in the incidence of common diseases such as heart disease, diabetes, stroke and certain cancers between British Asians and British Whites. However, there has been little research into why this is. We will conduct a study to investigate the causes of these differences.
March 2011 - March 2013
INDOX Cancer Research Network (University of Oxford)
There are known to be important differences in the incidence of common diseases such as heart disease, diabetes, stroke and certain cancers between British Asians and British Whites. For example, British Asians have been found to be more likely to develop diabetes and heart disease but less likely to develop certain cancers (eg bowel cancer). However, very little research has been undertaken to investigate the causes of these differences, especially with regard to cancer.
We will conduct a prospective cohort study of 250,000 British Asians to investigate the effects of diet and lifestyle on the risk of common diseases (particularly cancer but also heart disease, diabetes and stroke) amongst British Asians. The study will also allow us to compare differences in the incidence of these conditions between first and second generation migrants and the possible causes for these differences.
Investigate the effects of diet and lifestyle on the risk of common diseases amongst British Asians.
Activities» Examine impact of diet and lifestyle on incidence of cancer amongst British Asians.
» Examine impact of diet and lifestyle on incidence of heart disease amongst British Asians.
» Examine impact of diet and lifestyle on incidence of diabetes amongst British Asians.
» Examine impact of diet and lifestyle on incidence of stroke amongst British Asians.
Success will be identifying risk factors from diet and lifestyle that contribute towards lowering or increasing the incidence of cancer, heart disease, diabetes and stroke.
The findings of this study will have important public health implications not just for British Asians but even more significantly for the 1.5 billion South Asians in the sub-continent itself where people’s lifestyles are becoming increasingly ‘Westernized’. The results of this study could therefore be instrumental in reducing the risk of South Asian populations developing these diseases in the future and preventing needless suffering and deaths.
The main risk for the project is that we will not be able to recruit enough participants for the study. However, we have extensive experience in successful recruitment for research studies. We believe the UK is ideally suited to conduct such a study due to the NHS system (which allows all participants to be followed up and the incidence of disease to be accurately recorded) and indeed it is unlikely that such a study could be done anywhere else in the world.
Donors will receive an annual report about research progress and also a final report at the end of the study.
Budget - Project Cost: £250,000Loading graph....
Amount Heading Description £50,000 Protocol Development Development of the protocol for the study. £50,000 Training Training for researchers involved in conducting the study. £100,000 Recruitment Recruiting participants and conducting research. £50,000 Analysis of Result Analysing and publishing the results of the study.
The United Kingdom is home to one of the largest populations of people of South Asian origin outside the Indian sub-continent itself. Large numbers from India, Pakistan, Bangladesh and East Africa migrated to the UK from the 1950s to the 1980s and there now approximately 3 million ‘British Asians’ living in the UK (1st, 2nd and 3rd generation).
The findings of this study will have important public health implications not just for British Asians but even more significantly for the 1.5 billion South Asians whose lifestyles are becoming increasingly ‘Westernized’. This research will give an indication of what might happen in the future in South Asia.The results of this study could thus be instrumental in reducing the risk of South Asians developing these diseases in the future&preventing needless suffering and deaths.
Established in 2005 as a partnership between the Institute of Cancer Medicine at the University of Oxford & India's top ten comprehensive cancer centres, INDOX brings together many of the world’s leading cancer scientists in a unique global resource to conduct research into the prevention &treatment of cancer.This study will be conducted in partnership with the Cancer Epidemiology Unit at the University of Oxford which has one of the largest concentrations of epidemiological expertise worldwide.
Read more about the Charity running this project.
Professor Dame Valerie Beral - Co-Principal Investigator
Director of Cancer Epidemiology Unit & leads international collaborative studies of breast, ovarian and endometrial cancers at University of Oxford.
Dr Raghib Ali - Co-Principal Investigator
Director of the INDOX Cancer Research Network & conducts epidemiological studies in South Asia and the South Asian diaspora at University of Oxford.