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Breaking the epilepsy DNA code
Genomic sequencing can transform the lives of people with epilepsy, giving insights into the cause, personalized medication, and risks of Sudden Unexpected Death in Epilepsy (SUDEP). Our world leading professors provide the scientific and medical expertise to make real breakthroughs possible.
September 2017 - August 2020
Charity information: Epilepsy Society
Anyone can develop epilepsy, at any time of life. It happens in people of all ages, races and social classes. Epilepsy affects half million people in the UK, and every year 1000 people die from epilepsy, that’s eight people a day. Seizures and their treatment can be different for each person. There is no cure, and whilst some people can control their seizures through a cocktail of drugs the lives of others are severely impacted.
Genetics tell us more about a person’s epilepsy in a single test than any other source. We know we can transform the lives of many more people with epilepsy through groundbreaking whole genome sequencing. This will unlock the epilepsy DNA, let us develop personalized, more effective treatments, and reduce Sudden Unexpected Death in Epilepsy (SUDEP).
Sequence and analyse epilepsy patient DNA samples
Activities» Scientific laboratory research
What success will look like
DNA samples sequenced, and analysed.
DNA insights achieved through sequencing and analysis will allow us to develop improved treatments and personalised medicine for people with epilepsy, thereby reducing their seizures and the impact on their lives. We will be able to track this through patient records. It will also contribute to the body of research into sudden death in epilepsy enabling us to reduce the risk of incidence.
We have world leading epilepsy scientists and researchers who are best placed to undertake this research. A key risk to achieving the is lack of funding which we are addressing by launching this appeal
Examples of how we will report to donors are
- posting results on our web site
- links from facebook and twitter account to the web page
- email newsletters
- articles in our off-line supporter newsletters
- supporter events
Budget - Project Cost: £35,000Loading graph....
Amount Heading Description £35,000 Research genetic sequencing and analysis
The project will take place at the purpose built Epilepsy Society Research Centre based in Chalfont St Peter, Buckinghamshire, UK This is the largest medical charity in the field of epilepsy in the UK, providing services for people with epilepsy for over 100 years.
Epilepsy medical research gives us the best opportunity to transform and save thousands of lives. We believe that research represents the best hope of finding a cure for epilepsy, and eventually preventing it altogether.
Individuals whose DNA is sequenced will benefit most directly at first, as it will inform personalised treatment plans.
Everyone affected by epilepsy (ie 60m people worldwide) will benefit in the longer term as insights from genomic sequencing lead to scientific breakthroughs.
The Epilepsy Society is the largest medical charity in the field of epilepsy in the UK, providing services for people with epilepsy for over 100 years. We have purpose built treatment and research facilities on site and are acknowledged as a World Health Centre of Excellence. Professors, scientists and researchers are literally world leaders in this field https://www.epilepsysociety.org.uk/meet-our-research-team#.WV9uMTPMwnN
Read more about the Charity running this project.
Professor Sanjay Sisodiya
Professor Sisodiya is leading this research