Funding research to cure, treat and prevent type 1
JDRF’s research strategy is focused on moving scientific discoveries into products, drugs and treatments for those affected by type 1 diabetes. Our research strategy concentrating on four main areas: immune therapies, beta cell therapies, complications and control therapies.
Type 1 diabetes is a chronic, life-threatening autoimmune condition which has a lifelong impact on 400,000 people in the UK. Often striking in childhood, the condition causes the body’s own immune system to turn against insulin-producing cells, which are vital to allow the body to turn glucose from food into energy. Without insulin, glucose builds up in the blood and if left untreated can lead to a coma and ultimately death.
Together with research scientists and people affected by type 1 diabetes, we have developed a strategy to help us focus on the type 1 research that we think will make the biggest difference, now and in the future. We are at the forefront of numerous breakthroughs, and lead the way in innovative and vital research.
Cure – replace the destroyed beta cells and stop the immune system from attacking the new ones
Activities» Research to make transplants of insulin-producing cells more effective and suitable for more people, and to better understand the immune system
Finding ways to control the reaction at the heart of type 1 diabetes and restoring the ability to make insulin, in order to remove the burden of living with type 1.
Treat– improve the quality of life of people living with type 1 through better blood glucose control
Activities» The development of an artificial pancreas which would automatically manage a person's blood glucose levels.
Successfully finding ways to administer insulin and developing automatic systems that can control insulin delivery and blood glucose levels by itself.
Prevent – stopping the immune system from destroying the insulin-producing cells in the pancreas
Activities» Researching the causes of type 1 diabetes, to help us develop ways to protect people who are most likely to develop the condition.
Getting a better understanding of the ‘invisible’ steps in the body that happen before type 1 diabetes is diagnosed.
Our long term aim is to cure treat and prevent type 1 diabetes. To do this we fund lots of short projects that provide us with more information in our search for the cure. The results from our current projects will shape the future direction of our research as scientists prove or disprove particular avenues of research.
Each project will have specific aims and success will be measured by meeting those aims and contributing to the knowledge base of type 1 diabetes.
A risk associated with any medical research project is the loss of key staff. If this occurred there would be a short delay in the running of projects whilst the team recruited new members of staff to the project. Appropriate procedures are in place to manage other risks.
Researchers are required to produce annual progress and final research reports to JDRF. The reports are translated by our research communication team who make them accessible to a lay audience. We then share this information on our website & in our supporter magazine Type 1 Discovery.
Budget - Project Cost: £80,000Loading graph....
Amount Heading Description £80,000 Research Contributing directly to our research programme to cure, treat and prevent type 1 diabetes.
Our lab-based research in the UK is based at some of the top universities in the country. These universities have the facilities and expertise needed for scientists to be able to conduct research efficiently. We also fund research at some of the UK's top hospitals, since most of the clinical or patient-based research we fund needs to take place somewhere where patients can be monitored safely.
400,000 people in the UK have type 1 diabetes, including 29,000 children, and the rest of the world’s population with type 1 which the WHO estimates at 43m, will also benefit. JDRF is affiliated to JDRF International, which was first established in the United States in 1970. Today there are ten affiliated charities around the world and each operates independently. However, all of our research supports a joint international strategy that, we believe, will find the cure for type 1 most rapidly.
JDRF is totally focused on type 1 diabetes. We are the world’s leading charitable funder of type 1 research, and in the past 40 years we have funded £1 billion of the best research to cure, treat and prevent the disease. We work with academia, industry and governments to make sure that this research has the greatest possible impact on the lives of people with type 1 now and in the future.
Read more about the Charity running this project.
Principal Investigator of a project leads the research and has overall control over the design and management of the project.
Post Doctoral Fellow
Post Doctoral Fellow is a trained scientist who performs most of the experiments involved in a research project.
Research Nurses provide invaluable support and assistance to the people who volunteer to take part in research.
People Living With Type 1 Diabates
People with type 1 who volunteer to take part in clinical research.